The Chicago Area Patient-Centered Outcomes Research Network (CAPriCORN) is a clinical data research network of research institutions, clinicians, patients and patient advocates funded by the Patient-Centered Outcomes Research Institute (PCORI). 


MRAIA provides centralized infrastructure and technical support for CAPriCORN, serves as the data management hub, acts as an honest broker, and produces limited data analysis when required for multi-center research projects such as:


CAPriCORN Cohorts around weight management, asthma, anemia, recurrent Clostridium difficile, and sickle cell diseases. 


A Patient-centric Trial Assessing Benefits and Long-Terms Effectiveness (ADAPTABLE) - a clinical trial that compares the effectiveness of two daily doses of aspirin widely used to prevent heart attacks and strokes in individuals living with heart disease.

Obesity Trials:

  • Bariatrics observational study to examine benefits, complications, potential risks and other outcomes for the three common types of bariatric surgeries: gastric bypass, adjustable gastric banding, and sleeve gastrectomy.

  • Antibiotics study on childhood obesity to examine the relationship between antibiotic use in the first two years of life and weight gain in later childhood. 

Health Systems Demonstration Projects:

  • Evaluation of coding reliability of homelessness among Chicago region health care facilities and two Homeless Management Information Systems (HMIS).

  • The Natural Experiments for Translation in Diabetes (NEXT-D) is a study that examines how the Affordable Care Act expansion of Medicaid will affect diabetes diagnosis, treatment, and outcomes among the newly enrolled.

  • NCI Next Generation Cohort project investigates the history of invasive cancer between 2012-2017 for the identified population among the CAPriCORN Central hub team health centers.

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